Trinucleotide Diseases and Instability 87 2Kommunikationsprobleme

2Kommunikationsprobleme

waren die Urmenschen

um die Beziehungen zwischen den Akteuren einer Geschichte genauer erfassen zu können

als ausschlaggebender Erfolgsfaktor

Trinucleotide Diseases and Instability 87 2KommunikationsproblemeTill recently, mutations in genes were described in textbooks as deletions or point mutations. These mutations can be inherited from a parent or they are de novo alterations. The discovery in 1991 that human disease can be caused by large scale ex pansion of highly unstable trinucleotide repeats has elucidated a new mutation mechanism, heritable unstable DNA. In the subsequent years more then 10 such disease genes have been identified. All dynamic